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AttributesValues
rdf:type
rdfs:label
  • Vitamin K
rdfs:subClassOf
Has_NICHD_Parent
Concept_In_Subset
Semantic_Type
  • Lipid
  • Vitamin
Preferred_Name
  • Vitamin K
UMLS_CUI
  • C0042878
CAS_Registry
  • 12001-79-5
Contributing_Source
  • CRCH
  • NICHD
ALT_DEFINITION
  • Fat soluble vitamin that is a coenzyme during the synthesis of the biologically active form of a number of proteins involved in blood coagulation and bone metabolism. Vitamin K's structure typically consists of a methylated naphthoquinone ring from which one or more unsaturated aliphatic side chains are attached at the 3-position of the ring.CRCH
  • A nutrient that the body needs in small amounts to function and stay healthy. Vitamin K helps to form blood clots (a mass that forms when blood platelets, proteins, and cells stick together) and maintain strong bones. It is fat-soluble (can dissolve in fats and oils) and is found in green leafy vegetables, broccoli, liver, and vegetable oils. Vitamin K is also made by bacteria that live in the large intestine. Not enough vitamin K can lead to bleeding and bruising.NCI-GLOSS
Chemical_Formula
  • C31H46O2
US_Recommended_Intake
  • Y
INFOODS
  • VITK
USDA_ID
  • 430
Unit
  • mcg
Nutrient
  • Y
Micronutrient
  • Y
Legacy_Concept_Name
  • Vitamin_K
CHEBI_ID
  • CHEBI:28384
FULL_SYN
  • Vitamin KPTNICHD
  • Vitamin KPTNCI
  • 2-methyl-3-(3,7,11,15-tetramethylhexadec-2-enyl)naphthalene-1,4-dioneSYCRCH
  • vitamin KPTNCI-GLOSSCDR0000046044
  • Vitamin KPTCRCH
DEFINITION
  • The term "vitamin K" refers to a group of chemically similar fat-soluble compounds called naphthoquinones: vitamin K1 (phytonadione) is found in plants and is the primary source of vitamin K for humans through dietary consumption, vitamin K2 compounds (menaquinones) are made by bacteria in the human gut, and vitamin K3 (menadione) is a water-soluble preparation available for adults only. Vitamin K is necessary for the liver to produce the coagulation factors II, VII, IX, and X, as well as the clotting factors protein C, protein S, and protein Z; vitamin K deficiency can result in deficiencies of these coagulation factors and excess bleeding. An injection of vitamin K is routinely given to newborn infants to prevent vitamin K deficiency bleeding, also known as hemorrhagic disease of the newborn. Vitamin K deficiency is rare in adults but may result from chronic malnutrition or an inability to absorb dietary vitamins.NCI
code
  • C943
sameAs
http://linked.open...y/mesh/hasConcept
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