About: TP53INP1 wt Allele     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • TP53INP1 wt Allele
rdfs:subClassOf
OMIM_Number
  • 606185
GenBank_Accession_Number
  • AF409115
Semantic_Type
  • Gene or Genome
Preferred_Name
  • TP53INP1 wt Allele
UMLS_CUI
  • C2985139
EntrezGene_ID
  • 94241
HGNC_ID
  • HGNC:18022
FULL_SYN
  • DKFZp434M1317SYNCI
  • Tumor Protein p53 Inducible Nuclear Protein 1 wt AlleleSYNCI
  • SIPSYNCI
  • TeapSYNCI
  • TP53INP1 wt AllelePTNCI
  • FLJ22139SYNCI
  • p53DINP1SYNCI
  • TP53INP1ASYNCI
  • TP53INP1BSYNCI
  • TP53DINP1SYNCI
DEFINITION
  • Human TP53INP1 wild-type allele is located in the vicinity of 8q22 and is approximately 23 kb in length. This allele, which encodes tumor protein p53-inducible nuclear protein 1, is involved in the promotion of apoptosis in response to DNA damage. Aberrant expression of the gene is associated with pancreatic ductal adenocarcinomas and HTLV-related T cell leukemia.NCI
DesignNote
  • Expression of the TP53INP1 gene can be induced by adriamycin, gamma irradiation and hydrogen peroxide, in a p53-dependent way. Lower expression levels are induced by ultraviolet radiation. (UniProt)
  • The TP53INP1 gene has two distinct products that are the result of alternative splicing.
code
  • C92491
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