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AttributesValues
rdf:type
rdfs:label
  • Phagocytosis Pathway
rdfs:subClassOf
Semantic_Type
  • Functional Concept
Preferred_Name
  • Phagocytosis Pathway
UMLS_CUI
  • C2984574
KEGG_ID
  • hsa04145
ALT_DEFINITION
  • Phagocytosis is the process of taking in relatively large particles by a cell, and is a central mechanism in the tissue remodeling, inflammation, and defense against infectious agents. A phagosome is formed when the specific receptors on the phagocyte surface recognize ligands on the particle surface. After formation, nascent phagosomes progressively acquire digestive characteristics. This maturation of phagosomes involves regulated interaction with the other membrane organelles, including recycling endosomes, late endosomes and lysosomes. The fusion of phagosomes and lysosomes releases toxic products that kill most bacteria and degrade them into fragments. However, some bacteria have strategies to escape the bactericidal mechanisms associated with phagocytosis and survive within host phagocytes.KEGG
FULL_SYN
  • Phagocytosis PathwayPTNCI
  • PhagosomePTKEGG
code
  • C91809
is someValuesFrom of
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