About: Hedgehog Signaling Pathway

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Attributes	Values
rdf:type	Class
rdfs:label	Hedgehog Signaling Pathway
rdfs:subClassOf	Signaling Pathway
Semantic_Type	Functional Concept
Preferred_Name	Hedgehog Signaling Pathway
UMLS_CUI	C1155468
KEGG_ID	hsa04340
ALT_DEFINITION	The Hedgehog (Hh) family of secreted signaling proteins plays a crucial role in development of diverse animal phyla, from Drosophila to humans, regulating morphogenesis of a variety of tissues and organs. Hh signaling is also involved in control of stem cell proliferation in adult tissues and aberrant activation of the Hh pathway has been linked to multiple types of human cancer. Members of the Hh family bind to patched (ptc), thus releasing smoothened (smo) to transduce a signal. Transcriptional activation occurs through the GLI family of proteins resulting in activation of target genes.KEGG
FULL_SYN	Hedgehog Signaling PathwayPTNCI Hedgehog signaling pathwayPTKEGG
code	C91516
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