About: Calcium-Mediated Signaling Pathway

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About: Calcium-Mediated Signaling Pathway Goto Sponge NotDistinct Permalink

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Attributes	Values
rdf:type	Class
rdfs:label	Calcium-Mediated Signaling Pathway
rdfs:subClassOf	Signaling Pathway
Semantic_Type	Functional Concept
Preferred_Name	Calcium-Mediated Signaling Pathway
UMLS_CUI	C2984272
KEGG_ID	hsa04020
ALT_DEFINITION	Ca2+ that enters the cell from the outside is a principal source of signal Ca2+. Entry of Ca2+ is driven by the presence of a large electrochemical gradient across the plasma membrane. Cells use this external source of signal Ca2+ by activating various entry channels with widely different properties. The voltage-operated channels (VOCs) are found in excitable cells and generate the rapid Ca2+ fluxes that control fast cellular processes. There are many other Ca2+-entry channels, such as the receptor-operated channels (ROCs), for example the NMDA (N-methyl-D-aspartate) receptors (NMDARs) that respond to glutamate. There also are second-messenger-operated channels (SMOCs) and store-operated channels (SOCs).KEGG
FULL_SYN	Calcium-Mediated Signaling PathwayPTNCI Calcium signaling pathwayPTKEGG
code	C91460
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