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AttributesValues
rdf:type
rdfs:label
  • Lysosome Assembly Pathway
rdfs:subClassOf
Semantic_Type
  • Functional Concept
Preferred_Name
  • Lysosome Assembly Pathway
UMLS_CUI
  • C2984253
KEGG_ID
  • hsa04142
ALT_DEFINITION
  • Lysosomes are membrane-delimited organelles in animal cells serving as the cell's main digestive compartment to which all sorts of macromolecules are delivered for degradation. They contain more than 40 hydrolases in an acidic environment (pH of about 5). After synthesis in the ER, lysosomal enzymes are decorated with mannose-6-phosphate residues, which are recognized by mannose-6-phosphate receptors in the trans-Golgi network. They are packaged into clathrin-coated vesicles and are transported to late endosomes. Substances for digestion are acquired by the lysosomes via a series of processes including endocytosis, phagocytosis, and autophagy.KEGG
FULL_SYN
  • Lysosome Assembly PathwayPTNCI
  • LysosomePTKEGG
code
  • C91440
is someValuesFrom of
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