About: Phosphatidylcholine Biosynthesis Pathway     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
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  • Phosphatidylcholine Biosynthesis Pathway
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Semantic_Type
  • Functional Concept
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  • Phosphatidylcholine Biosynthesis Pathway
UMLS_CUI
  • C2984157
BioCarta_ID
  • pcsynthesispathway
ALT_DEFINITION
  • The main components of biological membranes are phosphoglyceride lipids composed of a glycerol unit esterified to two fatty acids and a polar alcohol group. The properties of phospholipids give lipid bilayer membranes their self-organizing structure. The polar alcohol group is hydrophilic and organizes itself in the membrane facing outward toward water, while the hydrophobic fatty acid alkyl chains face inward toward other fatty acid chains. One of the primary membrane phospholipids is phosphatidylcholine, in which the polar head group is composed of phosphocholine. The biosynthesis of phosphatidylcholine and phosphatidylethanolamine follow similar routes. The first step in phosphatidylcholine is the phosphorylation of choline to make phosphocholine, which is then activated by CTP. CDP-choline reacts with diacylglycerol to produce phosphatidylcholineBIOCARTA
FULL_SYN
  • Phosphatidylcholine Biosynthesis PathwayPTBIOCARTA
  • Phosphatidylcholine Biosynthesis PathwayPTNCI
code
  • C91316
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