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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Nicotine Lozenge
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Nicotine Lozenge
UMLS_CUI
  • C1171947
ALT_DEFINITION
  • A hard candy-like tablet that contains a small dose of nicotine. The nicotine is absorbed through the lining of the mouth and goes into the blood. This helps stop nicotine cravings, and relieves symptoms that occur when a person is trying to quit smoking. A prescription is not needed for nicotine lozenges.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 662920
PDQ_Closed_Trial_Search_ID
  • 662920
FULL_SYN
  • Nicotine LozengePTNCI
  • CommitBRNCI
  • nicotine lozengePTNCI-GLOSSCDR0000441271
DEFINITION
  • A lozenge preparation containing the alkaloid nicotine with nicotine replacement activity. Upon administration of the lozenge, nicotine is released and, although nicotine binds to nicotinic cholinergic receptors at the autonomic ganglia, adrenal medulla and at neuromuscular junctions as well, the binding of nicotine to the receptors in the central nervous system (CNS) appears to be responsible for the addictive nature of nicotine. Binding to CNS nicotinic acetylcholine receptors causes the release of the neurotransmitter dopamine which appears to be responsible for the addiction of nicotine. Administration of nicotine may prevent nicotine craving and may help with the withdrawal symptoms associated with smoking cessation.NCI
code
  • C90531
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