About: Levothyroxine Sodium     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Levothyroxine Sodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Levothyroxine Sodium
NSC_Code
  • 36397
UMLS_CUI
  • C0079691
CAS_Registry
  • 25416-65-3
FDA_UNII_Code
  • 9J765S329G
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 39117
PDQ_Closed_Trial_Search_ID
  • 39117
Chemical_Formula
  • C15H10I4NO4.Na.H2O
Legacy_Concept_Name
  • Therapeutic_Levothyroxine
FULL_SYN
  • LEVOTHYROXINE SODIUMPTFDA9J765S329G
  • Sodium levothyroxineSYDTPNSC0259940
  • Levothyroxine sodiumSYDTPNSC0259940
  • Therapeutic LevothyroxineSYNCI
  • Levothyroxine SodiumPTNCI
DEFINITION
  • The sodium salt of levothyroxine, a synthetic levoisomer of thyroxine (T4) that is similar to the endogenous hormone produced by the thyroid gland. In peripheral tissues, levothyroxine is deiodinated by 5'-deiodinase to form triiodothyronine (T3). T3 enters the cell and binds to nuclear thyroid hormone receptors; the activated hormone-receptor complex in turn triggers gene expression and produces proteins required in the regulation of cellular respiration; thermogenesis; cellular growth and differentiation; and the metabolism of proteins, carbohydrates and lipids. T3 also exhibits cardiostimulatory effects.NCI
code
  • C888
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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