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AttributesValues
rdf:type
rdfs:label
  • Recombinant Thymosin
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Recombinant Thymosin
UMLS_CUI
  • C1527153
CAS_Registry
  • 61512-21-8
In_Clinical_Trial_For
  • Hepatitis C; chronic hepatitis B; Solid Tumors.
ALT_DEFINITION
  • Thymosin. A family of heat-stable, polypeptide hormones secreted by the thymus gland. Their biological activities include lymphocytopoiesis, restoration of immunological competence and enhancement of expression of T-cell characteristics and function. They have therapeutic potential in patients having primary or secondary immunodeficiency diseases, cancer or diseases related to aging.MSH2002_06_01
PDQ_Open_Trial_Search_ID
  • 39716
PDQ_Closed_Trial_Search_ID
  • 39716
Legacy_Concept_Name
  • Recombinant_Thymosin
FULL_SYN
  • ThymosinSYNCI
  • Recombinant ThymosinPTNCI
DEFINITION
  • A recombinant form of a polypeptide chemically identical to or similar to the hormone secreted by the thymus gland. Thymosin is generally known to have functions in the preprocessing of T cells and the development of B cells to plasma cells to produce antibodies. In particular, the predominant form of thymosin, beta 4 thymosin, is the principal actin-sequestering protein that plays an important role in functions that involve actin molecules, such as maintenance of cell shape, cytoplasmic organization, cell movement, and cell division.NCI
code
  • C883
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