About: MDM4 wt Allele     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • MDM4 wt Allele
rdfs:subClassOf
OMIM_Number
  • 602704
GenBank_Accession_Number
  • AF007111
Semantic_Type
  • Gene or Genome
Preferred_Name
  • MDM4 wt Allele
UMLS_CUI
  • C2981745
EntrezGene_ID
  • 4194
HGNC_ID
  • HGNC:6974
FULL_SYN
  • MRP1SYNCI
  • DKFZp781B1423SYNCI
  • MDM4 wt AllelePTNCI
  • Mouse Double Minute 4, Human Homolog of; p53-Binding Protein GeneSYNCI
  • HDMXSYNCI
  • MDMXSYNCI
  • Mdm4, Transformed 3T3 Cell Double Minute 4, p53 Binding Protein (Mouse) GeneSYNCI
  • Mdm4 p53 Binding Protein Homolog (Mouse) wt AlleleSYNCI
  • MGC132766SYNCI
DEFINITION
  • NCIHuman MDM4 wild-type allele is located in the vicinity of 1q32 and is approximately 34 kb in length. This allele, which encodes protein Mdm4, is involved in cell cycle checkpoint regulation. Aberrant gene expression is associated with retinoblastoma.
DesignNote
  • The MDM4 gene may be a therapeutic target for cancers that have an unmutated TP53 gene.
code
  • C88219
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