About: Thioinosine

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Thioinosine
rdfs:subClassOf	Purine Antagonist IMMUNE SUPPRESSANTS
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance Nucleic Acid, Nucleoside, or Nucleotide
Preferred_Name	Thioinosine
NSC_Code	4911
UMLS_CUI	C0039904
CAS_Registry	574-25-4
FDA_UNII_Code	46S541971T
Contributing_Source	FDA
PDQ_Open_Trial_Search_ID	39496
PDQ_Closed_Trial_Search_ID	39496
Chemical_Formula	C10H12N4O4S
Legacy_Concept_Name	Thioinosine
FULL_SYN	ThioinosineSYDTPNSC0004911 ThioinosinePTNCI Mercaptopurine RibosideSYNCI ribosyl-6-mercaptopurineSNNCI 6-mercaptopurine ribosideSNNCI inosine, 6-thioSNNCI 6-Mercaptopurine ribonucleosideSYDTPNSC0004911 THIOINOSINEPTFDA46S541971T 6-mercaptopurine ribonucleosideSNNCI 6-Mercaptopurine ribosideSYDTPNSC0004911
DEFINITION	A sulfhydryl analog of inosine and an antimetabolite with potential antineoplastic and immunosuppressive properties. Thioinosine interferes with de novo purine synthesis and perturbs the pool of nucleotides necessary for DNA replication. As a result, this agent inhibits DNA synthesis, blocks cellular proliferation and induces apoptosis.NCI
code	C877
sameAs	Thioinosine
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0021358
is sameAs of	Thioinosine

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