About: Thiotepa

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Thiotepa
rdfs:subClassOf	Aziridines
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Pharmacologic Substance Organophosphorus Compound
Preferred_Name	Thiotepa
NSC_Code	6396
UMLS_CUI	C0039871
CAS_Registry	52-24-4
Accepted_Therapeutic_Use_For	Bladder cancer; Breast cancer; Ovarian cancer; Hodgkins lymphoma; Non-hodgkins lymphoma
In_Clinical_Trial_For	Brain cancer; Breast cancer; Malignant glioma; Primary central nervous system lymphoma
FDA_UNII_Code	905Z5W3GKH
Contributing_Source	FDA
ALT_DEFINITION	An anticancer drug that belongs to the family of drugs called alkylating agents.NCI-GLOSS
PDQ_Open_Trial_Search_ID	42933
PDQ_Closed_Trial_Search_ID	42933
Chemical_Formula	C6H12N3PS
Legacy_Concept_Name	Thiotepa
FULL_SYN	OncotiotepaSYDTPNSC0006396 TSPASYDTPNSC0006396 OncotiotepaFBNCI TESPASYDTPNSC0006396 STEPASYDTPNSC0006396 Onco TiotepaFBNCI ThiofosfamideSYNCI tris(1-aziridinyl)phosphine sulfideSNNCI TIO TEFSYDTPNSC0006396 1,1',1''-PhosphinothioylidynetrisaziridineSYDTPNSC0006396 Tris(1-aziridinyl)phosphine sulfideSYDTPNSC0006396 ThiophosphamideSYNCI Tio-tefSYDTPNSC0006396 TSPAABNCI ThiotefSYDTPNSC0006396 N,N',N''-triethylenethiophosphoramideSNNCI TifosylSYDTPNSC0006396 TriethylenethiophosphoramideSYDTPNSC0006396 THIOTEPAPTFDA905Z5W3GKH TESPAABNCI STEPABRNCI ThiophosphamideSYDTPNSC0006396 ThiotepaSYDTPNSC0006396 TespaminSYDTPNSC0006396 Triethylene thiophosphoramideSYDTPNSC0006396 GirostanSYDTPNSC0006396 ThiophosphoramideSYNCI triethylenethiophosphoramideSYNCI Thio-TepaSYDTPNSC0006396 Tio-TEFBRNCI ThiotefBRNCI TifosylBRNCI TespamineSYDTPNSC0006396 N,N', N''-TriethylenethiophosphoramideSYDTPNSC0006396 ThiofozilSYDTPNSC0006396 Triethylene ThiophosphoramideSYNCI WR 45312CNNCI thiotepaPTNCI-GLOSSCDR0000045603 TespaminFBNCI ThiotepaPTNCI GirostanBRNCI ThioplexBRNCI 1,1',1''-PhosphinothioyldynetrisaziridineSNNCI 1,1',1"-phosphinothioylidynetrisaziridineSNNCI Thio-TepaBRNCI LedertepaFBNCI TespamineFBNCI ThiofozilBRNCI ThiotepaPTDCP00340
DEFINITION	A synthetic alkylating agent. Related to nitrogen mustard, thiotepa alkylates and crosslinks DNA, resulting in the inhibition of DNA replication. (NCI04)NCI
code	C875
sameAs	THIOTEPA THIOTEPA
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0021343
is someValuesFrom of	nodeID://b645252 nodeID://b645262 nodeID://b645341 nodeID://b645369 nodeID://b646321 nodeID://b651916 nodeID://b651924 nodeID://b651938 nodeID://b651942 nodeID://b651947 nodeID://b656850 nodeID://b656864 nodeID://b656866 nodeID://b657007 nodeID://b657085 nodeID://b657110 nodeID://b657203 nodeID://b657322 nodeID://b657331 nodeID://b657334 nodeID://b657335 nodeID://b657537 nodeID://b657538 nodeID://b657639 nodeID://b657640 nodeID://b657693 nodeID://b659707

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