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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Demecarium
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Demecarium
UMLS_CUI
  • C0360174
FDA_UNII_Code
  • ILP8XJ8R5K
Contributing_Source
  • FDA
Chemical_Formula
  • C32H52N4O4
FULL_SYN
  • N,N'-Bis(3-Trimethylammoniumphenoxycarbonyl(-N,N'-DimethyldecamethylenediamineSNNCI
  • 3,3'-[1,10-Decanediylbis((Methylimino)Carbonyloxy))Bis(N,N,N-Trimethylbenzenaminium)SNNCI
  • DEMECARIUMPTFDAILP8XJ8R5K
  • Benzenaminium, 3,3'-(1,10-Decanediylbis((Methylimino)Carbonyloxy))Bis(N,N,N-Trimethyl-SNNCI
  • (M-Hydroxyphenyl)Trimethylammonium Decamethylenebis(Methylcarbamate)SNNCI
  • DemecariumPTNCI
DEFINITION
  • A quaternary ammonium compound that serves as a long-acting cholinesterase inhibitor with parasympathomimetic activity. When used topically, demecarium inactivates both pseudocholinesterase and acetylcholinesterase, thereby preventing acetylcholine breakdown and increasing acetylcholine activity. This causes contraction of the iris sphincter muscle (producing miosis) and the ciliary muscle (affecting the accommodation reflex). In so doing, this agent increases the outflow of the aqueous humor, thereby reducing intraocular pressure.NCI
code
  • C87481
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