About: Thiamine

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Thiamine
rdfs:subClassOf	B Vitamin
Has_Salt_Form	THIAMINE HYDROCHLORIDE
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Organic Chemical Vitamin
Preferred_Name	Thiamine
UMLS_CUI	C0039840
CAS_Registry	59-43-8
FDA_UNII_Code	X66NSO3N35
Contributing_Source	CRCH FDA
ALT_DEFINITION	3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2- hydroxyethyl)-4-methylthiazolium chloride.MSH2002_06_01 Water-soluble vitamin that is a coenzyme in the metabolism of carbohydrates and branched-chain amino acids. (DRI)CRCH A nutrient in the vitamin B complex that the body needs in small amounts to function and stay healthy. Vitamin B1 helps some enzymes work properly, helps break down sugars in the diet, and keeps nerves and the heart healthy. It is found in pork, organ meats, peas, beans, nuts, and whole grains. Vitamin B1 is water-soluble (can dissolve in water) and must be taken in daily. Not enough vitamin B1 can cause a disease called beriberi (a condition marked by heart, nerve, and digestive disorders). Too much vitamin B1 may help cancer cells grow faster.NCI-GLOSS
PDQ_Open_Trial_Search_ID	37856
PDQ_Closed_Trial_Search_ID	37856
Chemical_Formula	C12H17N4OS.Cl
US_Recommended_Intake	Y
INFOODS	THIA
USDA_ID	404
Unit	mg
Nutrient	Y
Micronutrient	Y
Legacy_Concept_Name	Thiamine
CHEBI_ID	CHEBI:33283
FULL_SYN	vitamin B1PTNCI-GLOSSCDR0000629163 Vitamin B1SYCRCH 2-[3-[(4-amino-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-1-thia-3-azoniacyclopenta-2,4-dien-5-yl]ethanolSYNCI THIAMINEPTFDAX66NSO3N35 Vit B1ABNCI ThiaminSYNCI thiaminePTNCI-GLOSSCDR0000556404 ThiaminPTCRCH ThiaminePTNCI AneurinSYCRCH ThiamineSYCRCH ThiaminePTDCP05001 B1 VitaminSYNCI Vitamin B1SYNCI Vitamin-B1SYNCI
DEFINITION	A heat-labile and water-soluble essential vitamin, belonging to the vitamin B family, with antioxidant, erythropoietic, mood modulating, and glucose-regulating activities. Thiamine reacts with adenosine triphosphate (ATP) to form an active coenzyme, thiamine pyrophosphate. Thiamine pyrophosphate is necessary for the actions of pyruvate dehydrogenase and alpha-ketoglutarate in carbohydrate metabolism and for the actions of transketolase, an enzyme that plays an important role in the pentose phosphate pathway. Thiamine plays a key role in intracellular glucose metabolism and may inhibit the action of glucose and insulin on arterial smooth muscle cell proliferation. Thiamine may also protect against lead toxicity by inhibiting lead-induced lipid peroxidation.NCI
code	C874
sameAs	THIAMINE THIAMINE
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0021318
is Has_Free_Acid_Or_Base_Form of	THIAMINE HYDROCHLORIDE
is sameAs of	THIAMINE THIAMINE THIAMINE THIAMINE

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