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AttributesValues
rdf:type
rdfs:label
  • Theophylline
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Theophylline
NSC_Code
  • 2066
UMLS_CUI
  • C0039771
CAS_Registry
  • 5967-84-0
FDA_UNII_Code
  • C137DTR5RG
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to improve breathing in people who are short of breath. It belongs to the family of drugs called bronchodilators or respiratory smooth muscle relaxants.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 41340
PDQ_Closed_Trial_Search_ID
  • 41340
Chemical_Formula
  • C7H8N4O2.H2O
Legacy_Concept_Name
  • Theophylline
FULL_SYN
  • THEOPHYLLINEPTFDAC137DTR5RG
  • THEOPHYLLINESYDTPNSC0002066
  • Slo-PhyllinBRNCI
  • 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dioneSNNCI
  • ElixophyllinSYDTPNSC0002066
  • TheophyllinePTNCI
  • ElixophyllinBRNCI
  • Somophyllin-TBRNCI
  • Theophylline MonohydrateSYNCI
  • 3,7-Dihydro-1,3-dimethyl-1H-purine-2,6-dione MonohydrateSNNCI
  • theophyllinePTNCI-GLOSSCDR0000045358
  • Theobid DuracapBRNCI
  • Somophyllin-CRTBRNCI
  • RespbidSYDTPNSC0002066
  • TheophyllinePTDCP00815
  • LaBIDBRNCI
  • T-PhylBRNCI
  • Theo-24BRNCI
  • Slo-bidBRNCI
  • RespbidBRNCI
  • UniphylBRNCI
  • TheochronBRNCI
  • Constant-TBRNCI
  • 1,3-Dimethylxanthine MonohydrateSNNCI
DEFINITION
  • A natural alkaloid derivative of xanthine isolated from the plants Camellia sinensis and Coffea arabica. Theophylline appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Physiologically, this agent relaxes bronchial smooth muscle, produces vasodilation (except in cerebral vessels), stimulates the CNS, stimulates cardiac muscle, induces diuresis, and increases gastric acid secretion; it may also suppress inflammation and improve contractility of the diaphragm. (NCI04)NCI
code
  • C872
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