About: Natural Killer Cells ZRx101     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Natural Killer Cells ZRx101
rdfs:subClassOf
Semantic_Type
  • Cell
  • Pharmacologic Substance
Preferred_Name
  • Natural Killer Cells ZRx101
NCI_META_CUI
  • CL412341
PDQ_Open_Trial_Search_ID
  • 643814
PDQ_Closed_Trial_Search_ID
  • 643814
FULL_SYN
  • NK Cells ZRx101SYNCI
  • Natural Killer Cells ZRx101PTNCI
DEFINITION
  • A population of activated, immortalized, interleukin-2 (IL-2)-dependent, cytotoxic natural killer (NK) cells with potential antitumor activity. Natural killer cells ZRx101 are derived from NK-92 cells, having been modified to target tumor-associated antigens (TAAs) upregulated in certain types of cancer. The NK-92 cell line was originally isolated from a patient with large granular lymphocytic (LGL) leukemia/lymphoma.NCI
code
  • C85466
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