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AttributesValues
rdf:type
rdfs:label
  • Sucralfate
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Carbohydrate
  • Pharmacologic Substance
Preferred_Name
  • Sucralfate
UMLS_CUI
  • C0038633
CAS_Registry
  • 54182-58-0
FDA_UNII_Code
  • XX73205DH5
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to treat ulcers. It adheres to proteins at the ulcer site and forms a protective coating over the ulcer. Sucralfate is also used to treat mucositis.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 39608
PDQ_Closed_Trial_Search_ID
  • 39608
Chemical_Formula
  • C12H30Al8O51S8.H2O.AlH3O3
Legacy_Concept_Name
  • Sucralfate
FULL_SYN
  • sucralfatePTNCI-GLOSSCDR0000045234
  • SUCRALFATEPTFDAXX73205DH5
  • CarafateBRNCI
  • SucralfatePTNCI
DEFINITION
  • A nonabsorbable, aluminum salt of sucrose orasulfate with anti-ulcer, mucosa-protective and potentially anti-mucositis activity. Negatively charged sucralfate binds, through ionic bond formation, to positively charged proteins on mucosal surfaces, thereby creating a protective coating and physical barrier. This agent may also enhance the production of prostaglandin E2 locally, thereby promoting mucus production, increasing mucosal blood flow and stimulating epithelial proliferation and may contribute to the healing of damaged mucosa.NCI
code
  • C848
sameAs
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