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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Idrapril
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Idrapril
UMLS_CUI
  • C0172867
CAS_Registry
  • 127420-24-0
FDA_UNII_Code
  • 176P5C4QU8
Contributing_Source
  • FDA
Chemical_Formula
  • C11H18N2O5
FULL_SYN
  • IDRAPRILPTFDA176P5C4QU8
  • IdraprilPTNCI
DEFINITION
  • A hydroxamic, non-amino acid derivative angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Idrapril competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Idrapril also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.NCI
code
  • C83780
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