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AttributesValues
rdf:type
rdfs:label
  • Filibuvir
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Filibuvir
UMLS_CUI
  • C2830151
CAS_Registry
  • 877130-28-4
FDA_UNII_Code
  • 198J479Y2L
Contributing_Source
  • FDA
Chemical_Formula
  • C29H37N5O3
FULL_SYN
  • (6R)-6-Cyclopentyl-6-(2-(2,6-Diethylpyridin-4-yl)Ethyl)-3-((5,7-Dimethyl(1,2,4)Triazolo(1,5- A)Pyrimidin-2-yl)Methyl)-4-Hydroxy-5,6-Dihydro-2H-Pyran-2-OneSNNCI
  • FILIBUVIRPTFDA198J479Y2L
  • FilibuvirPTNCI
  • 2H-Pyran-2-One, 6-Cyclopentyl-6-(2-(2,6-Diethyl-4-Pyridinyl)Ethyl)-3-((5,7-Dimethyl(1,2,4)Triazolo(1,5-A)Pyrimidin-2-yl)Methyl)-5,6-Dihydro-4-Hydroxy-, (6R)-SNNCI
  • PF-00868554CNNCI
DEFINITION
  • A non-nucleoside polymerase inhibitor of the hepatitis C virus NS5B RNA-dependent RNA polymerase. Filibuvir binds to the non-catalytic Thumb 2 site on viral polymerase and causes a decrease in viral RNA synthesis.NCI
code
  • C83717
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