About: MUC1 Peptide-Poly-ICLC Vaccine     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • MUC1 Peptide-Poly-ICLC Vaccine
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • MUC1 Peptide-Poly-ICLC Vaccine
UMLS_CUI
  • C2826163
PDQ_Open_Trial_Search_ID
  • 637356
PDQ_Closed_Trial_Search_ID
  • 637356
Legacy_Concept_Name
  • MUC1_Peptide_Vaccine-Poly-ICLC_Adjuvant
FULL_SYN
  • MUC1 Peptide-Poly-ICLC VaccinePTNCI
DEFINITION
  • A vaccine preparation containing mucus 1 (MUC1) peptide and the adjuvant poly-ICLC with potential immunostimulatory and antineoplastic activities. Upon administration, MUC1 peptide-poly-ICLC adjuvant vaccine may induce the host immune system to mount a cytotoxic T cell response against MUC1-expressing tumor cells. MUC1, a tumor associated antigen normally present on the lining of the human colon, may be overexpressed and/or mutated in a variety of cancer cell types. The adjuvant poly-ICLC, a ligand for toll-like receptor-3, induces the release of cytokines which may help boost the immune response against MUC1.NCI
code
  • C82417
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