About: Bone Metastasis Targeting Peptide-11     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Bone Metastasis Targeting Peptide-11
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Bone Metastasis Targeting Peptide-11
NCI_META_CUI
  • CL408646
PDQ_Open_Trial_Search_ID
  • 641166
PDQ_Closed_Trial_Search_ID
  • 641166
Legacy_Concept_Name
  • Bone_Metastasis_Targeting_Peptide-11
FULL_SYN
  • Bone Metastasis Targeting Peptide-11PTNCI
  • BMTP-11CNNCI
DEFINITION
  • A peptide that mimics naturally occurring interleukin-11 (IL-11) with interleukin receptor binding activity. Upon administration, bone metastasis targeting peptide-11 (BMTP-11) binds to interleukin-11 receptor alpha (IL-11Ra) BMTP-11. This agent might be used to deliver therapeutic agents specifically to IL-11Ra-expressing tumor cells while sparing normal cells. IL-11Ra is a cell surface receptor that may be overexpressed by osteosarcoma cells and by prostate cancer cells in prostate cancer bone metastases.NCI
code
  • C82370
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