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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Tavaborole
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Tavaborole
UMLS_CUI
  • C1743355
CAS_Registry
  • 174671-46-6
FDA_UNII_Code
  • K124A4EUQ3
Contributing_Source
  • FDA
Chemical_Formula
  • C7H6BFO2
Legacy_Concept_Name
  • _5-Fluoro-1_3-Dihydro-1-Hydroxy-2_1-Benzoxaborole
FULL_SYN
  • 5-Fluoro-1,3-Dihydro-1-Hydroxy-2,1-BenzoxaboroleSNNCI
  • AN2690CNNCI
  • TAVABOROLEPTFDAK124A4EUQ3
  • TavaborolePTNCI
DEFINITION
  • A boron-containing small molecule antifungal agent with broad-spectrum activity against filamentous fungi, including both mold and yeast. 5-Fluoro-1,3-dihydro-1-hydroxy-2,1-benzoxaborole inhibits fungal cytoplasmic leucyl-tRNA synthetase by preventing catalytic turnover, thus inhibiting synthesis of leucyl-tRNA(Leu) and consequentially blocking protein synthesis.NCI
code
  • C81725
http://linked.open...y/mesh/hasConcept
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