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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Pleconaril
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Pleconaril
UMLS_CUI
  • C0386613
CAS_Registry
  • 153168-05-9
FDA_UNII_Code
  • 9H4570Q89D
Contributing_Source
  • FDA
Chemical_Formula
  • C18H18F3N3O3
Legacy_Concept_Name
  • Pleconaril
FULL_SYN
  • 3-(4-(3-(3-Methyl-5-isoxazolyl)propoxy)-3,5-xylyl)-5-trifluoromethyl)-1,2,4-oxadizoleSNNCI
  • PicovirSYNCI
  • PLECONARILPTFDA9H4570Q89D
  • VP-63843CNNCI
  • Win-63843CNNCI
  • PleconarilPTNCI
DEFINITION
  • A small-molecule inhibitor with activity against viruses in the picornaviridae family, including enterovirus and rhinovirus. Pleconaril binds to a hydrophobic pocket in the major capsid protein and prevents uncoating of the viral RNA genome. In enteroviruses it also prevents the virus from attaching itself to the host cell.NCI
code
  • C81604
http://linked.open...y/mesh/hasConcept
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