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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Eprotirome
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Eprotirome
UMLS_CUI
  • C2825673
CAS_Registry
  • 355129-15-6
FDA_UNII_Code
  • 958AQ7B6R1
Contributing_Source
  • FDA
Chemical_Formula
  • C18H17Br2NO5
Legacy_Concept_Name
  • Eprotirome
FULL_SYN
  • EPROTIROMEPTFDA958AQ7B6R1
  • EprotiromePTNCI
DEFINITION
  • A thyroid hormone analog with hypocholesterolemic properties. Eprotirome reduces serum LDL cholesterol levels by increasing hepatic clearance due to increased expression of the hepatic LDL-receptor gene, and also reduces the serum level of Lp(a) lipoprotein. This drug was designed to have minimal uptake in nonhepatic tissues thereby avoiding many of the adverse effects associated with thyroid hormone treatment.NCI
code
  • C81533
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