About: Antihemophilic Factor, Human Recombinant     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Antihemophilic Factor, Human Recombinant
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Antihemophilic Factor, Human Recombinant
UMLS_CUI
  • C2732002
CAS_Registry
  • 139076-62-3
FDA_UNII_Code
  • P89DR4NY54
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 671261
PDQ_Closed_Trial_Search_ID
  • 671261
Legacy_Concept_Name
  • Antihemophilic_Factor_Human_Recombinant
FULL_SYN
  • Factor VIIISYNCI
  • FVIIIABNCI
  • ANTIHEMOPHILIC FACTOR, HUMAN RECOMBINANTPTFDAP89DR4NY54
  • Antihemophilic Factor, Human RecombinantPTNCI
DEFINITION
  • The recombinant form of human antihemophilic factor (AH)) (Factor VIII) with coagulation promoting activity. Antihemophilic factor binds to factor IXa in the coagulation cascade along with calcium and phospholipid. This complex converts factor X to the activated form, factor Xa. In turn, factor Xa/Va complex activates thrombin, which cleaves fibrinogen into fibrin, eventually resulting in blood clot formation.NCI
code
  • C81123
is sameAs of
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