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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Epicillin
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Epicillin
UMLS_CUI
  • C0059424
CAS_Registry
  • 26774-90-3
FDA_UNII_Code
  • 3LU1L73C8Y
Contributing_Source
  • FDA
Chemical_Formula
  • C16H21N3O4S
Legacy_Concept_Name
  • Epicillin
CHEBI_ID
  • CHEBI:58974
FULL_SYN
  • EPICILLINPTFDA3LU1L73C8Y
  • EpicillinPTNCI
DEFINITION
  • An extended-spectrum, semisynthetic aminopenicillin with antibacterial activity. Epicillin binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity. This interrupts bacterial cell wall synthesis and results in the weakening of the bacterial cell wall, eventually causing cell lysis.NCI
code
  • C80590
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