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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Noscapine
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Noscapine
NSC_Code
  • 5366
UMLS_CUI
  • C0028426
CAS_Registry
  • 128-62-1
FDA_UNII_Code
  • 8V32U4AOQU
Contributing_Source
  • FDA
Chemical_Formula
  • C22H23NO7
Legacy_Concept_Name
  • Noscapine
FULL_SYN
  • NOSCAPINEPTFDA8V32U4AOQU
  • NoscapinePTNCI
DEFINITION
  • A phthalide isoquinoline non-narcotic alkaloid derived from the opium poppy Papaver somniferum, with mild analgesic, antitussive, and potential antineoplastic activities. Noscapine exerts its antitussive effects through the activation of sigma opioid receptors. This agent appears to exert its antimitotic effect by binding to tubulin, resulting in a disruption of microtubule assembly dynamics and subsequently, the inhibition of mitosis and tumor cell death.NCI
code
  • C80589
sameAs
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