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AttributesValues
rdf:type
rdfs:label
  • Copper Gluconate
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Copper Gluconate
UMLS_CUI
  • C0982097
CAS_Registry
  • 527-09-3
FDA_UNII_Code
  • RV823G6G67
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 614606
PDQ_Closed_Trial_Search_ID
  • 614606
Chemical_Formula
  • 2C6H11O7.Cu
Legacy_Concept_Name
  • Copper_Gluconate
FULL_SYN
  • COPPER GLUCONATEPTFDARV823G6G67
  • Cupric GluconateSYNCI
  • Copper GluconatePTNCI
DEFINITION
  • The orally bioavailable copper salt of D-gluconic acid. In addition to its roles as an enzyme cofactor for cytochrome C oxidase and superoxide dismutase, copper forms complexes with the thiocarbamate disulfiram (DSF) forming DSF-copper complexes, which enhances the DSF-mediated inhibition of the 26S proteasome; proteasome inhibition may result in inhibition of cellular protein degradation, cessation of cell cycle progression, inhibition of cellular proliferation, and the induction of apoptosis in susceptible tumor cell populations.NCI
code
  • C80050
is sameAs of
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