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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Transthyretin
rdfs:subClassOf
OMIM_Number
  • 176300
Semantic_Type
  • Amino Acid, Peptide, or Protein
Preferred_Name
  • Transthyretin
UMLS_CUI
  • C0032923
Legacy_Concept_Name
  • Transthyretin
FULL_SYN
  • TransthyretinPTNCI
  • TTRSYNCI
  • TBPASYNCI
  • ATTRSYNCI
  • PrealbuminSYNCI
Swiss_Prot
  • P02766
DEFINITION
  • Transthyretin (147 aa, ~16 kDa) is encoded by the human TTR gene. This protein is involved in both the binding and transport of retinol and thyroxine.NCI
DesignNote
  • Transthyretin is a homotetramer with two thyroxine binding sites. Less than 1% of plasma transthyretin is involved in thyroxine transport, while 40% is in a tight protein-protein complex with the plasma retinol-binding protein (RBP). The formation of the complex with RBP stabilizes the binding of retinol to RBP and decreases the glomerular filtration and renal catabolism of the RBP molecule. (UniProt)
code
  • C79964
sameAs
http://linked.open...y/mesh/hasConcept
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