About: Carbenicillin Phenyl Sodium     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Carbenicillin Phenyl Sodium
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Carbenicillin Phenyl Sodium
UMLS_CUI
  • C0085959
CAS_Registry
  • 21649-57-0
FDA_UNII_Code
  • 18N5JP36GY
Contributing_Source
  • FDA
Chemical_Formula
  • C23H21N2O6S.Na
Legacy_Concept_Name
  • Carbenicillin_Phenyl_Sodium
CHEBI_ID
  • CHEBI:34612
FULL_SYN
  • 4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-((1,3-dioxo-3-phenoxy-2-phenylpropyl)amino)-3,3-dimethyl-7-oxo-, monosodium salt, (2S-(2alpha,5alpha,6beta))SNNCI
  • Carbenicillin Phenyl SodiumPTNCI
  • UticillinBRNCI
  • CARBENICILLIN PHENYL SODIUMPTFDA18N5JP36GY
DEFINITION
  • The sodium salt of the phenyl ester of carbenicillin, a broad-spectrum, semisynthetic penicillin derivative with antibacterial activity. Following absorption, carbenicillin phenyl sodium is rapidly hydrolyzed to the active carbenicillin, which binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to a weakening of the bacterial cell wall, eventually causing bacterial cell lysis.NCI
code
  • C79421
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