About: WT1-A10/AS01B Immunotherapeutic GSK2130579A

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: WT1-A10/AS01B Immunotherapeutic GSK2130579A Goto Sponge NotDistinct Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	WT1-A10/AS01B Immunotherapeutic GSK2130579A
rdfs:subClassOf	Peptide Vaccine
Semantic_Type	Amino Acid, Peptide, or Protein Pharmacologic Substance
Preferred_Name	WT1-A10/AS01B Immunotherapeutic GSK2130579A
NCI_META_CUI	CL387745
PDQ_Open_Trial_Search_ID	610132
PDQ_Closed_Trial_Search_ID	610132
Legacy_Concept_Name	WT1_Vaccine_GSK2130579A
FULL_SYN	WT1-A10/AS01B Immunotherapeutic GSK2130579APTNCI GSK2130579ACNNCI
DEFINITION	An immunotherapeutic consisting of the recombinant fusion protein WT1-A10 combined with the adjuvant ASO1B with potential immunostimulating and antineoplastic activities. Upon administration, WT1-A10/AS01B immunotherapeutic GSK2130579AWT1 may induce a WT1-specific cytotoxic T-lymphocyte (CTL) response against WT1-expressing tumor cells, resulting in cell lysis and the inhibition of cellular proliferation. The tumor-associated antigen WT1 (Wilms tumor protein-1) is overexpressed in most types of leukemia and in a variety of solid cancers. WT1-A10 is a 292 amino acid recombinant fusion protein consisting of a 12-mer truncated tat sequence (leader sequence) and amino acids number 2-281 of the WT1 sequence; ASO1B consists of a combination of the adjuvants monophosporyl lipd A (MPL) and Q21.NCI
code	C78865

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 46 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software