About: Bevirimat Dimeglumine     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Bevirimat Dimeglumine
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Bevirimat Dimeglumine
UMLS_CUI
  • C2698386
CAS_Registry
  • 823821-85-8
FDA_UNII_Code
  • O6DDV91W1M
Contributing_Source
  • FDA
Chemical_Formula
  • C36H56O6.2C7H17NO5
Legacy_Concept_Name
  • Bevirimat_Dimeglumine
FULL_SYN
  • BEVIRIMAT DIMEGLUMINEPTFDAO6DDV91W1M
  • PA-457 di-NMGCNNCI
  • 3-(3-Carboxy-3-methyl-1-oxobutoxy)-, (3-beta)-, compd. with 1-deoxy-1-(methylamino)-D-glucitol (1:2)SYNCI
  • PA103001CNNCI
  • MPC-4326CNNCI
  • Bevirimat DimegluminePTNCI
DEFINITION
  • A dimeglumine formulation of bevirimat, a drug derived from a betulinic acid-like compound, first isolated from the Chinese herb Syzygium claviflorum, with activity against human immunodeficiency virus (HIV). Bevirimat acts by binding to the Gag capsid precursor protein and blocking its conversion to mature capsid protein by protease cleavage. It potently inhibits replication in both wild-type and drug-resistant (reverse transciptase or protease) HIV-1 isolates.NCI
code
  • C78045
is Has_Salt_Form of
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