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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Rivaroxaban
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Rivaroxaban
UMLS_CUI
  • C1739768
CAS_Registry
  • 366789-02-8
Accepted_Therapeutic_Use_For
  • Deep Vein Thrombosis Prophylaxis
FDA_UNII_Code
  • 9NDF7JZ4M3
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 701565
PDQ_Closed_Trial_Search_ID
  • 701565
Chemical_Formula
  • C19H18ClN3O5S
Legacy_Concept_Name
  • Rivaroxaban
FULL_SYN
  • RivaroxabanPTNCI
  • XareltoBRNCI
  • 5-Chloro-N-(((5S)-2-oxo-3-(4-(3-oxomorpholin-4-yl)phenyl)- 1,3-oxazolidin-5-yl)methyl)thiophene-2-carboxamideSNNCI
  • RIVAROXABANPTFDA9NDF7JZ4M3
  • BAY 59-7939CNNCI
DEFINITION
  • An orally bioavailable oxazolidinone derivative and direct inhibitor of the coagulation factor Xa with anticoagulant activity. Upon oral administration, rivaroxaban selectively binds to both free factor Xa and factor Xa bound in the prothrombinase complex. This interferes with the conversion of prothrombin (factor II) to thrombin and eventually prevents the formation of cross-linked fibrin clots. Rivaroxaban does not affect existing thrombin levels.NCI
code
  • C77995
sameAs
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