About: Prochlorperazine     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Prochlorperazine
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Organic Chemical
  • Pharmacologic Substance
Preferred_Name
  • Prochlorperazine
UMLS_CUI
  • C0033229
CAS_Registry
  • 58-38-8
Accepted_Therapeutic_Use_For
  • Anxiety; Dizziness; Nausea and vomiting management; Psychosis
FDA_UNII_Code
  • YHP6YLT61T
Contributing_Source
  • FDA
ALT_DEFINITION
  • A drug used to prevent or reduce nausea and vomiting. It belongs to the family of drugs called antiemetics.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 39564
PDQ_Closed_Trial_Search_ID
  • 39564
Chemical_Formula
  • C20H24ClN3S
Legacy_Concept_Name
  • Prochlorperazine
CHEBI_ID
  • CHEBI:8435
FULL_SYN
  • PROCHLORPERAZINEPTFDAYHP6YLT61T
  • ProchlorperazinePTNCI
  • RP 6140CNNCI
  • SKF-4657CNNCI
  • 2-Chloro-10-(3-(1-methyl-4-piperazinyl)propyl)-phenothiazineSNNCI
  • prochlorperazinePTNCI-GLOSSCDR0000045232
DEFINITION
  • A synthetic propylpiperazine derivative of phenothiazine with antiemetic, antipsychotic, antihistaminic, and anticholinergic activities. Prochlorperazine antagonizes the dopamine D2-receptor in the chemoreceptor trigger zone (CTZ) of the brain and may prevent chemotherapy-induced emesis. (NCI04)NCI
code
  • C774
sameAs
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