About: CF-1 Mouse     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • CF-1 Mouse
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Mammal
Preferred_Name
  • CF-1 Mouse
UMLS_CUI
  • C2698722
Contributing_Source
  • CDISC
ALT_DEFINITION
  • Thought to be wild albino in origin, this strain was obtained by Carworth farms from a Missouri laboratory. It was intensely inbred by N. Goto in 1978 from a single Carworth pair, the progeny of which is used today. The CF-1 mouse has an albino coat with genotype c.CDISC
Legacy_Concept_Name
  • CF-1_Mouse
FULL_SYN
  • CF-1SYNCI
  • CF-1PTCDISC
  • CF-1 MousePTNCI
DEFINITION
  • Thought to be wild albino in origin, this strain was obtained by Carworth farms from a Missouri laboratory. It was intensely inbred by N. Goto in 1978 from a single Carworth pair, the progeny of which is used today. The CF-1 mouse has an albino coat with genotype c and is used as a multi-purpose strain for a variety of applications including infectious disease modeling, embryological studies, and safety and efficacy testing. In this mouse model, cleft palate formation can be induced by cortisone while alloxan treatment induces diabetes in a high percentage of CF-1 mice.NCI
code
  • C77116
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