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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Abciximab
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Immunologic Factor
Preferred_Name
  • Abciximab
UMLS_CUI
  • C0288672
CAS_Registry
  • 143653-53-6
Accepted_Therapeutic_Use_For
  • as an adjunct to aspirin and heparin for the prevention of acute cardiac ischemic complications
FDA_UNII_Code
  • X85G7936GV
Contributing_Source
  • FDA
Legacy_Concept_Name
  • Abciximab
FULL_SYN
  • Chimeric 7E3 FabSYNCI
  • ABCIXIMABPTFDAX85G7936GV
  • ReoProBRNCI
  • MoAb 7E3ABNCI
  • AbciximabPTNCI
DEFINITION
  • A Fab fragment of the chimeric monoclonal antibody 7E3 and inhibitor of the glycoprotein (GP) IIb/IIIa receptor, that blocks platelet aggregation. Abciximab binds to the GP IIb/IIIa receptor on the platelet membrane, which inhibits the binding of fibrinogen to the GP IIb/IIIa receptor. This prevents both platelet aggregation and thrombus formation.NCI
code
  • C76128
sameAs
http://linked.open...y/mesh/hasConcept
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