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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Temocaprilat
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Temocaprilat
UMLS_CUI
  • C0646101
CAS_Registry
  • 110221-53-9
FDA_UNII_Code
  • 2D6A12Q12R
Contributing_Source
  • FDA
Chemical_Formula
  • C21H24N2O5S2
Legacy_Concept_Name
  • Temocaprilat
FULL_SYN
  • TEMOCAPRILATPTFDA2D6A12Q12R
  • TemocaprilatPTNCI
DEFINITION
  • An angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Temocaprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II and results in vasodilation. Temocaprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow.NCI
code
  • C75023
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