About: Piperacillin Sodium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Piperacillin Sodium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Antibiotic
  • Organic Chemical
Preferred_Name
  • Piperacillin Sodium
UMLS_CUI
  • C0700463
CAS_Registry
  • 59703-84-3
FDA_UNII_Code
  • M98T69Q7HP
Contributing_Source
  • FDA
ALT_DEFINITION
  • Semisynthetic, broad-spectrum, ampicillin-derived ureidopenicillin antibiotic proposed for Pseudomonas infections. It is also used in combination with other antibiotics.MSH2002_06_01
PDQ_Open_Trial_Search_ID
  • 39555
PDQ_Closed_Trial_Search_ID
  • 39555
Chemical_Formula
  • C23H26N5O7S.Na
Legacy_Concept_Name
  • Piperacillin
CHEBI_ID
  • CHEBI:8233
FULL_SYN
  • T-1220CNNCI
  • Piperacillin SodiumPTNCI
  • PipracilBRNCI
  • PIPERACILLIN SODIUMPTFDAM98T69Q7HP
  • Sodium (2S,5R,6R)-6-((R)-2-(4-ethyl-2,3-dioxo-1-piperazinecarboxamido)-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylateSNNCI
  • CL 227, 193CNNCI
DEFINITION
  • The sodium salt of piperacillin, a broad-spectrum semisynthetic, ampicillin-derived ureidopenicillin antibiotic with bactericidal activity. Piperacillin binds to and inactivates penicillin-binding proteins (PBPs), enzymes located on the inner membrane of the bacterial cell wall, resulting in the weakening of the bacterial cell wall and cell lysis. PBPs participate in the terminal stages of assembling the bacterial cell wall, and in reshaping the cell wall during cell division. Inactivation of PBPs interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity.NCI
code
  • C749
sameAs
http://linked.open...y/mesh/hasConcept
is someValuesFrom of
is Has_Salt_Form of
is sameAs of
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