About: Tiomolibdate Diammonium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Tiomolibdate Diammonium
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Tiomolibdate Diammonium
NSC_Code
  • 286644
  • 714598
UMLS_CUI
  • C0076339
CAS_Registry
  • 15060-55-6
FDA_UNII_Code
  • 4V6I63LW1E
Contributing_Source
  • FDA
ALT_DEFINITION
  • A substance being studied in the treatment of many types of cancer. Ammonium tetrathiomolybdate removes extra copper from the body. Removing the copper may prevent the growth of new blood vessels that tumors need to grow and may kill cancer cells. Ammonium tetrathiomolybdate is a type of chelating agent and a type of antiangiogenesis agent.NCI-GLOSS
PDQ_Open_Trial_Search_ID
  • 467218
PDQ_Closed_Trial_Search_ID
  • 467218
Chemical_Formula
  • MoS4.2H4N
Legacy_Concept_Name
  • Ammonium_Tetrathiomolybdate
FULL_SYN
  • Tiomolibdate DiammoniumPTNCI
  • TIOMOLIBDATE DIAMMONIUMPTFDA4V6I63LW1E
  • Molybdate(2-), Tetrathioxo-, Diammonium, (T-4)-SNNCI
  • ATTMABNCI
  • Ammonium Molybdenum SulfideSYNCI
  • Ammonium TetrathiomolybdateSYNCI
  • ammonium tetrathiomolybdatePTNCI-GLOSSCDR0000599961
  • CoprexaBRNCI
  • Diammonium TetrathiomolybdateSYNCI
  • Molybdate(2-), Tetrathioxo-, Ammonium (1:2), (T-4)-SNNCI
DEFINITION
  • An ammonium salt with potential antiangiogenic and antitumor activities. Tetrathiomolybdate has been found to deplete systemic copper reserves through an unknown mechanism. This agent has been shown to inhibit the activities of cuproenzymes, including superoxide dismutase 1 (SOD1) and cytochrome c oxidase (COX), which may contribute to its antiangiogenic and antitumor effects.NCI
code
  • C74001
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