About: Raltegravir Potassium     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Raltegravir Potassium
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Raltegravir Potassium
UMLS_CUI
  • C1967563
CAS_Registry
  • 871038-72-1
FDA_UNII_Code
  • 43Y000U234
Contributing_Source
  • FDA
PDQ_Open_Trial_Search_ID
  • 658548
PDQ_Closed_Trial_Search_ID
  • 658548
Chemical_Formula
  • C20H20FN6O5.K
Legacy_Concept_Name
  • Raltegravir_Potassium
FULL_SYN
  • RALTEGRAVIR POTASSIUMPTFDA43Y000U234
  • IsentressBRNCI
  • N-[(4-Fluorophenyl)methyl]-1,6-dihydro-5-hydroxy-1-methyl-2-[1-methyl-1-[[ (5-methyl-1,3,4-oxadiazol-2-yl)carbonyl]amino]ethyl]-6-oxo-4-pyrimidinecarboxamide Monopotassium SaltSNNCI
  • Raltegravir PotassiumPTNCI
DEFINITION
  • The orally bioavailable potassium salt of a human immunodeficiency virus (HIV) integrase strand transfer inhibitor (HIV-1 INSTI) with HIV-1 antiviral activity. Raltegravir binds to and inhibits integrase, an HIV enzyme that inserts viral genetic material into the genetic material of the infected human cell. Inhibition of integrase prevents insertion of HIV DNA into the human DNA genome, thus blocking HIV replication.NCI
code
  • C73823
sameAs
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
is sameAs of
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