About: Bisnafide Dimesylate     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Bisnafide Dimesylate
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Bisnafide Dimesylate
UMLS_CUI
  • C2347031
CAS_Registry
  • 145124-30-7
FDA_UNII_Code
  • J30IBO0LMA
Contributing_Source
  • FDA
Chemical_Formula
  • C32H28N6O8.2CH4O3S
Legacy_Concept_Name
  • Bisnafide_Dimesylate
FULL_SYN
  • Bisnafide DimesylatePTNCI
  • BISNAFIDE DIMESYLATEPTFDAJ30IBO0LMA
DEFINITION
  • The dimesylate salt form of bisnafide, a bis-naphthalimide compound with anticancer activity. Bisnafide selectively intercalates guanine-cytosine (GC) rich regions of DNA, thereby interfering with DNA replication machinery and activity of topoisomerase II. As a result, this agent causes potent cytotoxicity.NCI
code
  • C73307
is Has_Salt_Form of
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