About: Emivirine     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Emivirine
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Emivirine
UMLS_CUI
  • C0248121
CAS_Registry
  • 149950-60-7
FDA_UNII_Code
  • X87G8IX72O
Contributing_Source
  • FDA
Chemical_Formula
  • C17H22N2O3
Legacy_Concept_Name
  • Emivirine
CHEBI_ID
  • CHEBI:44143
FULL_SYN
  • 6-benzyl-1-(ethoxymethyl)-5-isopropyl-uracilSYNCI
  • EMVSYNCI
  • EMIVIRINEPTFDAX87G8IX72O
  • MKC-442SYNCI
  • CoactinonBRNCI
  • EmivirinePTNCI
DEFINITION
  • A non-nucleoside reverse transcriptase inhibitor. Emivirine has a structure typical of a nucleoside analog but has been shown to bind directly to the reverse transcriptase and act as an NNRTI. However, it is no longer in development due to the fact that it causes an increasingly rapid breakdown of other drugs metabolized by the cytochrome P450 enzyme.NCI
code
  • C73147
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