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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Darapladib
rdfs:subClassOf
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Darapladib
UMLS_CUI
  • C2348075
CAS_Registry
  • 356057-34-6
FDA_UNII_Code
  • UI1U1MYH09
Contributing_Source
  • FDA
Chemical_Formula
  • C36H38F4N4O2S
Legacy_Concept_Name
  • Darapladib
FULL_SYN
  • DARAPLADIBPTFDAUI1U1MYH09
  • SB 480848CNNCI
  • GSK480848CNNCI
  • DarapladibPTNCI
DEFINITION
  • A substituted pyrimidone with inhibitory activity towards lipoprotein-associated phospholipase-A2 (Lp-PLA2), an important regulator of lipid metabolism and inflammation that circulates with lipoprotein particles and is carried into the arterial wall with low-density lipoprotein particles during the progression of atherosclerosis.NCI
code
  • C72985
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