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AttributesValues
rdf:type
rdfs:label
  • Capreomycin
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Capreomycin
UMLS_CUI
  • C0262964
CAS_Registry
  • 11003-38-6
FDA_UNII_Code
  • 232HYX66HC
Contributing_Source
  • FDA
Legacy_Concept_Name
  • Capreomycin
CHEBI_ID
  • CHEBI:3371
FULL_SYN
  • CapreomycinPTNCI
  • Capreomycin ComplexSYNCI
  • CAPREOMYCINPTFDA232HYX66HC
DEFINITION
  • A cyclic polypeptide isolated from Streptomyces capreolus with antitubercular activity. Even though the exact mechanism by which capreomycin exerts its effect has yet to be fully elucidated, this agent may bind to the bacterial 50S subunit of the 70S ribosome. This leads to interference with the translational initiation complex, misreading of mRNA, and eventually leads to inhibition of protein synthesis. In addition, capreomycin also binds bacterial cell wall components thereby inhibiting cell wall synthesis.NCI
code
  • C72607
sameAs
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