About: Cytarabine Hydrochloride     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:label
  • Cytarabine Hydrochloride
rdfs:subClassOf
Has_Free_Acid_Or_Base_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
  • Nucleic Acid, Nucleoside, or Nucleotide
Preferred_Name
  • Cytarabine Hydrochloride
NSC_Code
  • 63878
UMLS_CUI
  • C0282120
CAS_Registry
  • 69-74-9
FDA_UNII_Code
  • 33K3DB6591
Contributing_Source
  • FDA
Chemical_Formula
  • C9H13N3O5.HCl
Legacy_Concept_Name
  • Cytarabine_Hydrochloride
FULL_SYN
  • Arabinosylcytosine HydrochlorideSYNCI
  • Cytosine Arabinosine HydrochlorideSYNCI
  • Cytarabine HydrochloridePTNCI
  • Aracytidine HydrochlorideSYNCI
  • CYTARABINE HYDROCHLORIDEPTFDA33K3DB6591
  • 1-Beta-D-arabinofuranosylcytosine HydrochlorideSNNCI
  • 4-Amino-1-beta-D-arabinofuranosyl-2(1H)-pyrimidinone HydrochlorideSNNCI
  • U-19920ACNNCI
  • CHX-3311CNNCI
  • Ara-C HClABNCI
  • Cytosar HydrochlorideBRNCI
  • Cytosar HydrochlorideSYNCI
DEFINITION
  • The hydrochloride form of cytarabine, an antimetabolite analogue of cytidine with a modified sugar moiety (arabinose instead of ribose). Cytarabine is converted to the triphosphate form within the cell and then competes with cytidine for incorporation into DNA. Because the arabinose sugar sterically hinders the rotation of the molecule within DNA, DNA replication ceases, specifically during the S phase of the cell cycle. This agent also inhibits DNA polymerase, resulting in a decrease in DNA replication and repair.NCI
code
  • C71603
http://linked.open...y/mesh/hasConcept
is Has_Salt_Form of
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 18 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software