About: Octreotide

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An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Octreotide
rdfs:subClassOf	Somatostatin Receptor Agonists
Has_Salt_Form	Octreotide Pamoate Octreotide Acetate
Concept_In_Subset	FDA Established Names and Unique Ingredient Identifier Codes Terminology
Semantic_Type	Amino Acid, Peptide, or Protein Pharmacologic Substance
Preferred_Name	Octreotide
PubMedID_Primary_Reference	16917205
UMLS_CUI	C0028833
CAS_Registry	83150-76-9
Accepted_Therapeutic_Use_For	Acromegaly; Diarrhea
FDA_UNII_Code	RWM8CCW8GP
Contributing_Source	FDA
ALT_DEFINITION	A drug similar to the naturally occurring growth hormone inhibitor somatostatin. Octreotide is used to treat diarrhea and flushing associated with certain types of tumors.NCI-GLOSS
Chemical_Formula	C49H66N10O10S2
Legacy_Concept_Name	Octreotide
CHEBI_ID	CHEBI:7726
FULL_SYN	octreotidePTNCI-GLOSSCDR0000045141 D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol Cyclic (2->7)-DisulfideSNNCI D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hyroxymethyl)propyl]-L-cysteinamide, Cyclic (2->7)-disulfidePTDCP02189 OCTREOTIDEPTFDARWM8CCW8GP D-Phenylalanyl-L-cysteinyl-L-phenyl-alanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide Cyclic (2->7)-DisulfideSNNCI SMS-201-995CNNCI OctreotidePTNCI
DEFINITION	A synthetic long-acting cyclic octapeptide with pharmacologic properties mimicking those of the natural hormone somatostatin. Octreotide is a more potent inhibitor of growth hormone, glucagon, and insulin than somatostatin. Similar to somatostatin, this agent also suppresses the luteinizing hormone response to gonadotropin-releasing hormone, decreases splanchnic blood flow, and inhibits the release of serotonin, gastrin, vasoactive intestinal peptide (VIP), secretin, motilin, pancreatic polypeptide, and thyroid stimulating hormone.NCI
code	C711
sameAs	OCTREOTIDE
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0023526
is someValuesFrom of	nodeID://b660076 nodeID://b667649 nodeID://b673729 nodeID://b673796 nodeID://b684381 nodeID://b697847 nodeID://b697850
is Has_Free_Acid_Or_Base_Form of	Octreotide Pamoate Octreotide Acetate
is sameAs of	OCTREOTIDE OCTREOTIDE

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