About: Renal Cell Carcinoma Peptides Vaccine IMA901     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Renal Cell Carcinoma Peptides Vaccine IMA901
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
  • Immunologic Factor
Preferred_Name
  • Renal Cell Carcinoma Peptides Vaccine IMA901
NCI_META_CUI
  • CL375872
In_Clinical_Trial_For
  • Renal Cell Carcinoma
PDQ_Open_Trial_Search_ID
  • 570963
PDQ_Closed_Trial_Search_ID
  • 570963
Legacy_Concept_Name
  • Renal_Cell_Carcinoma_Peptides_Vaccine_IMA901
FULL_SYN
  • Renal Cell Carcinoma Peptides Vaccine IMA901PTNCI
  • IMA901CNNCI
DEFINITION
  • A multipeptide cancer vaccine targeting renal cell carcinoma with potential immunopotentiating activity. Renal cell carcinoma peptides vaccine IMA901 consists of 10 different synthetic tumor-associated peptide (TUMAP) antigens (9 HLA-class I-binding and 1 HLA class II-binding); endogenously, these TUMAPs are expressed by the majority of renal cell carcinomas. Vaccination with this agent may significantly increase host cytotoxic T-lymphocyte (CTL) immune responses against tumor cells expressing these peptide antigens.NCI
code
  • C70968
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