About: Aurora Kinase Inhibitor SNS-314

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About: Aurora Kinase Inhibitor SNS-314 Goto Sponge NotDistinct Permalink

An Entity of Type : owl:Class, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	Class
rdfs:label	Aurora Kinase Inhibitor SNS-314
rdfs:subClassOf	Aurora Kinase Inhibitor nodeID://b647631 nodeID://b647632 nodeID://b647633 nodeID://b647634
Has_Target	Aurora Kinase A
Semantic_Type	Pharmacologic Substance
Preferred_Name	Aurora Kinase Inhibitor SNS-314
UMLS_CUI	C2346877
PDQ_Open_Trial_Search_ID	570599
PDQ_Closed_Trial_Search_ID	570599
Legacy_Concept_Name	Aurora_Kinase_Inhibitor_SNS-314
FULL_SYN	SNS-314CNNCI Aurora Kinase Inhibitor SNS-314PTNCI
DEFINITION	A synthetic small molecule Aurora kinase (AK) inhibitor with potential antineoplastic activity. Aurora kinase inhibitor SNS-314 selectively binds to and inhibits AKs A and B, which may result in the inhibition of cellular division and proliferation in tumor cells that overexpress AKs. AKs are serine-threonine kinases that play essential roles in mitotic checkpoint control during mitosis.NCI
code	C70655
http://linked.open...y/mesh/hasConcept	http://linked.opendata.cz/resource/mesh/concept/M0526126

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