About: Adenovirus Encoding Human Aquaporin-1     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Adenovirus Encoding Human Aquaporin-1
rdfs:subClassOf
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Adenovirus Encoding Human Aquaporin-1
NCI_META_CUI
  • CL374275
PDQ_Open_Trial_Search_ID
  • 547184
PDQ_Closed_Trial_Search_ID
  • 547184
Legacy_Concept_Name
  • Adenovirus_Encoding_Human_Aquaporin-1
FULL_SYN
  • Adenovirus Encoding Human Aquaporin-1PTNCI
  • AdhAQP1ABNCI
DEFINITION
  • A replication-deficient, recombinant adenovirus encoding human aquaporin-1 with potential membrane water channel activity. Upon transfection of salivary glands, adenovirus encoding human aquaporin-1 (AdhAQP1) directs human aquaporin-1 (hAQP1) expression in the apical and basolateral plasma membranes of salivary secretory cells, which may result in increased saliva production. hAQP1, a water channel protein, is one of several highly conserved water channel proteins that mediate water permeability in cells of water-transporting tissues.NCI
code
  • C68932
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